(-)-Epicatechin is most commonly used as a workout supplement as it may support follistatin volume, which hinders myostatin signaling, thus allowing (-)-Epicatechin to indirectly promote muscle growth. However, (-)-Epicatechin has some lesser known benefits to cognition as well. Several reports indicate that (-)-Epicatechin can help promote blood flow and has notable benefits to cognitive tasks like memory and executive function.

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